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Browsing Tag

Endoplasmic reticulum

3 posts

ALS Development Linked to Disruption of Mitochondria-Associated Membranes

Scientists at Nagoya University in Japan have unveiled a connection between the advancement of amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig's disease, and the disturbance observed in mitochondria-associated membranes (MAM). These MAMs serve as the critical junctions where mitochondria and the endoplasmic reticulum (ER) of the cell come into contact.

Eukaryotic Cell

Eukaryotic cells are a fundamental unit of life characterized by a complex structure. They contain a defined nucleus enclosed in a membrane, along with various organelles, such as mitochondria and the endoplasmic reticulum. These cells are found in plants, animals, fungi, and protists, and their compartmentalized structure allows for specialized functions. Eukaryotic cells are integral to multicellular organisms and exhibit a level of complexity that distinguishes them from prokaryotic cells.

Decoding the Endoplasmic Reticulum: Unraveling its Structure, Functions, and Implications in Diseases

The Endoplasmic Reticulum (ER) is a crucial organelle in eukaryotic cells responsible for protein synthesis, folding, and transport. It consists of a complex network of interconnected membranes, including rough ER with ribosomes and smooth ER without ribosomes. The ER plays a vital role in maintaining cellular homeostasis, lipid metabolism, and calcium storage. Dysfunctions in ER function can lead to various diseases, highlighting the significance of understanding its mechanisms and functions.